Takalani Sesame is the South African co-production of the global children's TV brand, Sesame Street. It is a flagship SABC Education series and the best-recognized education brands in South Africa. Using trademark Muppets and unique African characters, Takalani Sesame has captured the imagination of South African children for more than a decade with entertaining, engaging and age appropriate stories.

Learning can be fun! The series takes a holistic approach to early learning and development by integrating education and entertainment and implementing clear educational objectives in the fields of literacy, numeracy and life skills. These objectives are informed by the National South African ECD Curriculum.

Takalani Sesame is produced in partnership with the Department of Education, United States Agency for International Development Sanlam and SABC Education, and is under the creative direction of Sesame Workshop, New York.

Takalani Sesame has also had a special focus on HIV/Aids awareness and seeks to promote tolerance and reduce stigma: a world first was the introduction of an HIV Muppet, Kami. The series incorporates all of South Africa's eleven national languages: Afrikaans, English, isiNdebele, isiXhosa, isiZulu, Sepedi, Sesotho, Setswana, SiSwati, Tshivenda and Xitsonga. Archbishop Desmond Tutu, Kofi Annan, and Nane Annan have made guest appearances on the show.